Bacterial endocarditis of mitral valve in Marfan syndrome.

Bacterial endocarditis of mitral valve in Marfan syndrome.

An unusual case of bacterial endocarditis in Marfan syndrome is reported. A review of the published reports revealed 21 previously reported cases. The aortic valve, though commonly abnormal in Marfan syndrome, was rarely involved by the endocarditis. In contrast, the mitral valve was the favoured site of infection in these patients. Our own patient had staphylococcal endocarditis of both the ao...

Marfan syndrome and mitral valve prolapse.

Mitral valve prolapse (MVP), an abnormal displacement into the left atrium of a thickened and redundant mitral valve during systole, is a relatively frequent abnormality in humans and may be associated with serious complications. A recent study implicates fibrillin-1, a component of extracellular matrix microfibrils, in the pathogenesis of a murine model of MVP. This investigation represents an...

Conservative surgery of the mitral valve in bacterial endocarditis.

Surgical repair of the mitral valve was undertaken in two young female patients during the active phase of bacterial endocarditis to eradicate persistent infection. Operation resulted in rapid resolution of infection with good haemodynamic results in both patients. A mitral valve prosthesis has the disadvantage for children of needing replacement because of growth, and for young women of leadin...

Mitral valve aneurysm in endocarditis.

To the Editor: I read with interest the contribution by Cai et al in the “Images in Cardiovascular Medicine” section of the journal.1 They described a patient who developed severe aortic regurgitation and a mitral valve aneurysm 1 month after successful treatment of Streptococcus mitis endocarditis. The case presentation and the title implied that the mitral valve aneurysm was caused by the eff...

Bacterial Endocarditis Occurring on a Double Mitral Valve.